Scientists Seek Help With New Osteoporosis Treatment

Friday, March 1, 2002

Scientists Seek Help With New Osteoporosis Treatment (NAPSA)—Investigators across the country are recruiting participants for a clinical trial program to study the effectiveness of a new once yearly treatment for osteoporosis called zoledronic acid. Osteoporosis has reached epidemic proportions. One out of two American women and one of eight American men aged 50 and over will experience an osteoporosis-related bone fracture in This is the first program to study a once-yearly treatmentfor osteoporosis g The trials, known as HoRIZON given once for Paget’s disease. “Patients need new options that treat bone diseases like osteoporosis,” said Meryl S. LeBoff, M.D., director of skeletal health and osteoporosis at Brigham and Women’s Hospital in Boston and associate professor of medicine at Harvard Medical School. “We urge women and men whohaveosteoporosis or Paget’s disease to speak with their doctors about the condition and consider participating in patients. The Horizon trials are like no Researchers are seeking women between the ages of 65 and 89 who have osteoporosis, men and women aged 50 and over who have a history of a low-traumahip fracture but could walk prior to the their lifetime. This bone-thinning disease now affects 10 million Americans. New, more convenient treatments are needed for this debilitating disease. (Health Outcomes and Reduced Incidence with Zoledronic Acid ONceYearly), are being conducted in 400 trial centers over four continents with approximately 11,000 other studies ever conducted. This is the first program to study a onceyearly treatment for osteoporosis, and the first program to study the prevention of future fractures in patients who have already experienced an osteoporosis-related hip fracture. In addition, it is the first to study a single dose treatment one of the Horizonclinicaltrials.” fracture, and men and women aged 30 years or older who have Paget’s disease. If you match these criteria and are interested in volunteering for any of the Horizon studies, call 1-877-YHORIZON(1- 877-946-7496) or visit the Website at www.horizon.novartis.com for more information.

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